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Nombre de programmes trouvés : 1794
Conférences

le (26m40s)

Dr Rodrigo Guabiraba - Precision cut lung slices: a novel versatile tool to examine host–pathogen interactions in the chicken lung

The avian respiratory tract is a common entry route for many pathogens and an important delivery route for vaccination in the poultry industry. Immune responses in the avian lung have mostly been studied in vivo due to the lack of robust, relevant in vitro and ex vivo models mimicking the mucosal microenvironment. Various principles of microbial infection including pathogen tropism, replication, spread, and innate antimicrobial host responses can readily be studied in suitable cell or tissue culture models. Precision-cut lung slices (PCLS) have the major advantages of maintaining the 3-dimensional architecture ...
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Conférences

le (26m1s)

Dr Mustapha Si-Tahar - Towards a metabolic anti-influenza therapy

Influenza A virus (IAV) is the etiological agent of a contagious acute respiratory disease, which is associated with high morbidity and mortality. This virus also causes a considerable socio-economic burden despite annual vaccination campaigns. To help design innovative antiviral therapies, it is essential to better understand IAV-host cells interaction. In that regard, recent studies revealed the interplay between metabolic and immune signaling pathways. In this communication, I will present evidence that IAV alters lung tissues metabolism and I will show its functional consequence. Remarkably, we recently identified one metabolite that accumulates ...
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Conférences

le (45m51s)

Prof Régis Gougeon - Messages in a bottle: from oenolomics to the structural resolution of the transient chemistry of wine aging

Metabolomics applied to vine and wine sciences, has significantly developed over the last ten years. To that respect, high-resolution mass spectrometry has clearly shown unprecedented capability based on ultra-high resolving power and mass measurement accuracy. The introduction of the concept of oenolomics, exemplified by the metabologeography expression of cooperage oak wood in bottle-aged wines, further paved the way for breakthrough investigations of specific chemical fingerprints of wines, considered as transient molecular memories of vineyard-related environmental parameters and/or enological practices, which may have driven their original composition. We thus reported a ...
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Conférences

le (35m58s)

Dr Paweł Siudem - Aronia melanocarpa Fruits as a Dietary Source of bioactive compounds: 1H‑NMR, HPLC-DAD, and Chemometric Studies

Aronia melanocarpa (Michx.) Elliott's (chokeberry) it is well known for the presence of anthocyanins. The fruits also  contain significant amounts of other bioactive compounds, such as chlorogenic acid and its isomer neochlorogenic acid. They exhibit antioxidant, anti-inflammatory, antidiabetic, and antibacterial activities; thus, they can have a significant impact on the health-promoting properties of chokeberry. In our research, we have determined the changes in the content of chlorogenic acids (CGA) and anthocyanins during the development and ripening of fruits. Aronia fruit samples from two organic farms in Poland, were collected every two weeks ...
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Conférences

le (34m33s)

Prof. Angela Arthington - Progress with environmental flows to maintain healthy rivers and healthy societies

The science and practical applications of environmental flows (e-flows) have advanced rapidly since the early 1980s. E-flows serve as a means to protect the flow regimes and ecosystems of undeveloped rivers, and conversely, as a means to restore the flow regimes and ecological health of regulated rivers. From simple beginnings in the form of ‘minimum flows’ to ensure adequate aquatic habitat for fish, the e-flows concept has expanded to embrace the water requirements of rivers and other aquatic habitats as ecosystems. “Holistic” ecosystem methods aim to devise a flow regime that will ...
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Conférences

le (28m59s)

Prof. Karl Wantzen - Development(s) of the River Culture Concept

Rivers give rhythm to all life in their catchments. Floods and droughts trigger both, etho-physiological adaptations by biota, resulting in biodiversity, and one species, H. sapiens, resulting in cultural diversity. The River Culture Concept (2016) takes an attempt to re-establish harmony between humans and rivers. The five tenets of the concept include, (i)  reconsidering priorities on the use of riverine assets, (ii) integrating the natural flow regime into river management, (iii) rediscovering traditional ecological knowledge (and by no means all ancient use forms), (iv) copying natural adaptive strategies (“ecosystem bionics”), and ...
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Conférences

le (31m18s)

Dr Simone Langhans - Weaving together plural values in freshwater management: a case study of the Upper Clutha catchment in Aotearoa New Zealand

Public participation is an effective way to resolve the tensions between contested objectives, while maintaining ecological integrity. New Zealand is one of the few countries that takes a collaborative approach to environmental management, mandating that management plans for catchments are co-created with local communities based on the concept te Mana o te Wai. The National Policy Statement for Freshwater Management (NPS-FM) gives guidelines on objectives and attributes that must be considered to safeguard freshwater values. They also specify minimum quality standards, but allow communities to set higher standards and to add more ...
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Conférences

le (28m35s)

Dr Fengzhi He & Dr Rebecca Tharme - Freshwater megafauna: diversity, status, and cultural importance

Megafauna species play important ecological roles. Owing to their intrinsic characteristics such as large habitat requirements, long lifespan, and late maturity they are particularly susceptible to extinction. Freshwater megafauna species, i.e. freshwater animals that can reach a body mass of 30 kg or more, are also vulnerable to anthropogenic impacts. There are intense and growing threats such as overexploitation, dam construction, habitat degradation, pollution, and biological invasions in diversity hotspots of freshwater megafauna including the Amazon, Congo, Mekong, and Ganges-Brahmaputra river basins. Consequently, half of all assessed species are considered as ...
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Conférences

le (22m0s)

Dr Nathalie Richards - From the Mau Forest to Lake Victoria: The Journey of the Mara River in East Africa

The Mara River starts its journey in the Mau forest in Kenya, flowing through diverse waterscapes and famous savannahs into Tanzania, where it reaches the Mara wetland system before spilling into Lake Victoria. The landscapes surrounding the Mara River are shaped by the seasonality of its flows. Its exceptional flora and fauna follow the rhythm of water availability, and human inhabitants have adapted to and influenced the ecosystem services provided by the local environment. For millennia and more intensively in the past centuries, different peoples have been inspired by the river ecosystem ...
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