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Nombre de programmes trouvés : 7606
Conférences

le (27m34s)

Prof. Kingston Mills - Local T cells and their subversion in protective immunity to infection in the respiratory tract

Respiratory infection with Bordetella pertussis causes whooping cough. The infection is controlled by innate immune responses, but complete bacterial clearance from the respiratory tract and protection against re-infection is mediated largely by Th1 and Th17 cells. However the bacteria has evolved sophisticated immune subversion strategies to subvert these responses Antigen-specific regulatory T (Treg) cells that secrete IL-10 are induced in the respiratory tract during B. pertussis infection and suppress protective T cell responses. Pertussis disease can be prevented in children by immunization with acellular pertussis (aP) vaccines. However, aP vaccines ...
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Conférences

le (30m35s)

Prof. Pieter Hiemstra - Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects

Antimicrobial host defence peptides (AMPs) are effector molecules of the immune system. AMPs are considered as possible alternatives to conventional antibiotics for the treatment of respiratory infections, which is increasingly complicated by the problem of microbial antibiotic resistance. AMPs are also referred to as antimicrobial peptides and host defence peptides, and many AMPs were discovered based on their antimicrobial activity against a range of micro-organisms. However, they also display other activities that are relevant for host defence, including activities related to immune modulation and wound repair. Application of AMPs (and improved ...
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Conférences

le (26m40s)

Dr Rodrigo Guabiraba - Precision cut lung slices: a novel versatile tool to examine host–pathogen interactions in the chicken lung

The avian respiratory tract is a common entry route for many pathogens and an important delivery route for vaccination in the poultry industry. Immune responses in the avian lung have mostly been studied in vivo due to the lack of robust, relevant in vitro and ex vivo models mimicking the mucosal microenvironment. Various principles of microbial infection including pathogen tropism, replication, spread, and innate antimicrobial host responses can readily be studied in suitable cell or tissue culture models. Precision-cut lung slices (PCLS) have the major advantages of maintaining the 3-dimensional architecture ...
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Conférences

le (30m8s)

Dr Guido Santos - Multi-level computational modeling as a tool to understand molecular mechanisms behind bacterial lung infection

Pneumonia is one of the most prevalent infectious diseases worldwide, whose main cause is the pathogen Streptococcus pneumoniae. This is an opportunistic disease affecting the most to sensitive groups (infants, elderly and immunosuppressed people). In these patients the inflammatory response generated in the lungs is the main risk factor that happens in the very first days of infection. Under this situation the main goal is finding therapeutical or preventive strategies that are able to cut the inflammatory response as soon as possible.  In order to identify possible molecular targets to ...
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Conférences

le (44m14s)

Prothèses et humains augmentés

Du 27 au 28 juin 2020, l'équipe organisatrice du Bordeaux Geek Festival a transposé son événement en virtuel en raison des conditions sanitaires liées à l'épidémie du Covid-19. Sur la plateforme VirBELA, les festivaliers se sont vus proposer de multiples interventions aux thématiques diverses (prothèses, histoire du "geek", science-fiction, etc.). Devenu le Bordeaux Geekfest Virtual Experience le temps d'un week-end, la salle Enedis by Club Arthur Dent a accueilli diverses conférences comme celles proposées par les étudiants-chercheurs et partenaires de la Chaire RESET, partenaire pionnier de l'événement. Double lauréat des bourses du Comité d'Histoire de l'Électricité et de l'Énergie de la Fondation ...
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