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Nombre de programmes trouvés : 7598

le (1h19m33s)

Amphithéàtre d’information sur le Coronavirus COVID-19

Amphithéàtre d’information sur le Coronavirus COVID-19 (4 mars 2020)Point sur l’évolution de la situation épidémiologique, les mesures de protection et la prise en charge.avecProfesseur Pierre Hausfater, Chef des urgences / APHP Pitié-SalpêtrièreProfesseur Eric Caumes, Chef du service d’immunologie / APHP Pitié-SalpêtrièreProfesseur Jérôme Robert, Chef du service bactériologie et hygiène hospitalière / APHP Pitié-Salpêtrière
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le (30m35s)

Prof. Pieter Hiemstra - Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects

Antimicrobial host defence peptides (AMPs) are effector molecules of the immune system. AMPs are considered as possible alternatives to conventional antibiotics for the treatment of respiratory infections, which is increasingly complicated by the problem of microbial antibiotic resistance. AMPs are also referred to as antimicrobial peptides and host defence peptides, and many AMPs were discovered based on their antimicrobial activity against a range of micro-organisms. However, they also display other activities that are relevant for host defence, including activities related to immune modulation and wound repair. Application of AMPs (and improved ...
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le (26m40s)

Dr Rodrigo Guabiraba - Precision cut lung slices: a novel versatile tool to examine host–pathogen interactions in the chicken lung

The avian respiratory tract is a common entry route for many pathogens and an important delivery route for vaccination in the poultry industry. Immune responses in the avian lung have mostly been studied in vivo due to the lack of robust, relevant in vitro and ex vivo models mimicking the mucosal microenvironment. Various principles of microbial infection including pathogen tropism, replication, spread, and innate antimicrobial host responses can readily be studied in suitable cell or tissue culture models. Precision-cut lung slices (PCLS) have the major advantages of maintaining the 3-dimensional architecture ...
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le (30m8s)

Dr Guido Santos - Multi-level computational modeling as a tool to understand molecular mechanisms behind bacterial lung infection

Pneumonia is one of the most prevalent infectious diseases worldwide, whose main cause is the pathogen Streptococcus pneumoniae. This is an opportunistic disease affecting the most to sensitive groups (infants, elderly and immunosuppressed people). In these patients the inflammatory response generated in the lungs is the main risk factor that happens in the very first days of infection. Under this situation the main goal is finding therapeutical or preventive strategies that are able to cut the inflammatory response as soon as possible.  In order to identify possible molecular targets to ...
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