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Nombre de programmes trouvés : 2027
Conférences

le (9m11s)

Innovation reimbursement

Interface technology/clinical/SHS/public health : case study interventional radiology Novel diagnostic and therapeutic strategies is a continuum of 3 strongly associated phases : clinical research, medico-economic evaluation of a novel strategy and deployment of innovation, the last one being a field of competence of centers of expertise such as SIRIC BRIO.In the full cycle of innovation, the money time is the major challenge of a large deployment. The main problem is to find money. But, in 2015, 3 changes should improve the innovation continuum. Should it be a progress, an obstacle, or both ?...Cette présentation a été donnée dans ...
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Conférences

le (15m1s)

Standardizing G8 evaluation

Non-pharmaceutical innovations and public healthManagement of the frail elderly with cancer is a challenge. Beside a poor outcome as compared to younger subjects, physicians will face increased risk of treatment-induced toxicity but also unexpected adverse events because of the underlying comorbidities and potential major consequences of these toxicities on the outcome because of frailty. In depth evaluation of the patient through geriatric assessment has been demonstrated as predictive of these adverse events but is time-consuming so that only a minority of cancer treatment hospitals will be able to propose it. Screening is part of the solution and G8 one of ...
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Conférences

le (19m53s)

Curing leukemia ?

Non-pharmaceutical medical innovations and public healthThe use of tyrosine kinase inhibitors (TKIs) targeted against the BCR-ABL1 oncoprotein has proven remarkably successful in chronic myeloid leukemia (CML) and long-term survival has become a reality. Despite this outstanding progress, detection of minimal residual disease precludes therapy termination in most TKI-receiving patients. CML has thus turned into a chronic illness, raising concerns about long-term safety, medication adherence and healthcare costs. Although treatment cessation may be feasible in few selected patients achieving deep molecular responses, a definitive cure remains elusive owing to the discovery that TKIs spare quiescent leukemic stem cells (LSC). Understanding mechanisms ...
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Conférences

le (13m9s)

Multisarc

Translational science : how to move from biology to clinical applications Soft-tissues sarcomas represent an heterogeneous group of tumors. Stadard of care is surgical resection followed by radiotherapy. Patients with metastatic relapse are treated with chemotherapy but the overall survival is only approximatly 18 months. Actual research try to define new therapeutic targets, adapted to the type of sarcoma. The personalized medicine project aims to propose to patients with advanced sarcoma a targeted therapy based on the genomic and immunilogical profile. The main difference with other projects resides in ...
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Conférences

le (18m24s)

A new preclinical model to test the response of breast cancer to genomically targeted therapy

Translational science : how to move from biology to clinical applicationsThe rapid progress in next generation DNA sequencing technology (NGS) means it is now possible, in principle, to obtain a complete list of the genetic abnormalities in a tumour. In practice, clinicians use NGS to obtain a much shorter list of "actionable" mutations that can be targeted with available drugs or used as prognostic markers. Unfortunately, the mere presence of an actionable mutation does not guarantee a response to the cognate drug, as shown by the SAFIR1 study (André et al 2014). To spare patients unnecessary exposure to experimental drugs, ...
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Conférences

le (13m29s)

BRIO support to scientists

BRIO management team was voluntarily built upon various competencies from different horizons (industry, charity…) to provide a broad skillset which aims at supporting the Bordeaux cancer research community. In this section, BRIO highlights the core support the team can bring to scientists. First, in an era of decreasing and competitive public funds, we look into other funding sources, such as European funds where BRIO and the University can assist in finding and applying to the right call for proposals. Considering the current trends of pharma R&D externalisation, a favorable environment exists to partner with the industry to develop new drugs ...
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Documentaires

le (19m31s)

Chirurgie de la hernie discale cervicale avec pose de prothèse en ambulatoire

Ce film a été réalisé pour montrer le parcours d’une patiente opérée d’une hernie cervicale en ambulatoire avec ablation et pose de prothèse. Dans ce type de chirurgie, l'intervention en ambulatoire est une indication qui doit être très précise : sujet jeune, opéré à un seul niveau, ceci afin d’éviter une complication post-opératoire qui empêcherait le retour à domicile de la patiente.
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Label UNT Documentaires

le (15m30s)

Pose d'un cathéter veineux central par voie sous-clavière

Ce film pédagogique reprend les recommandations de bonnes pratiques et les principaux effets indésirables associés à la pose d'un cathéter veineux central par voie sous-clavière.Une revue complète de la littérature a permis de reprendre les différentes complications (mécaniques, infectieuses ou thrombotiques) et les moyens de prévention à mettre en oeuvre pour limiter le risque iatrogène.Film réalisé avec le soutien de l'UNF3S (projet M1102)2e prix du pôle "spécialités médicales", festival du film médical d'Amiens, FILMED 2010.
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Conférences

le (36m16s)

What the present and future hold for pulmonary MRI in early life

Over the past ten years, Bio-Imaging translational research has experienced an unprecedented expansion:  ten years of challenges, collaborations, success stories and significant advances, thanks to the combination of various approaches and disciplines. To celebrate  the anniversary of the LabEx TRAIL the community organizes a special online event mixing videos and live sessions with to-notch scientists.Imaging the future is the occasion for specialists of the bio-imaging field and more broadly for the whole academic community to take part in a discussion about the science of tomorrow. ...
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Conférences

le (53m47s)

Imagerie et Intelligence artificielle

Over the past ten years, Bio-Imaging translational research has experienced an unprecedented expansion: ten years of challenges, collaborations, success stories and significant advances, thanks to the combination of various approaches and disciplines. To celebrate the anniversary of the LabEx TRAIL the community organizes a special online event mixing videos and live sessions with to-notch scientists.Imaging the future is the occasion for specialists of the bio-imaging field and more broadly for the whole academic community to take part in a discussion about the science ...
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