This work explores whether evolving phages on diverse bacteria make them universally effective. Directed evolution of a Tequatrovirus phage on a genetically diverse bacterial population of E. coli

Enteric viruses like noroviruses commonly contaminate shellfish and cause gastroenteritis. Due to the absence of a routine culture method for noroviruses, F-specific RNA bacteriophages (FRNAPH) are

Our study focuses on developing vials with antibiofouling coatings to prevent bacteriophage adsorption. PEG-like and zwitterion compounds are explored as promising films on glass and silicon

This study re-evaluated the mutation rate of phage lambda and its host, E. coli. It confirmed lambda's higher mutation rate but found that mismatch repair (MMR) inefficiency due to Dam methylation

This study explores the horizontal transfer of a type I-F CRISPR-Cas system from Pseudomonas aeruginosa to Pseudomonas fluorescens. While functional in the new host, its protective benefits depend on

Mycobacterium abscessus is a multidrug-resistant bacterium causing severe infections in cystic fibrosis patients, where phage therapy shows promise as an alternative treatment. Testing phages on

Evolution of a virulent Tequintavirus leads to an expansion in its host range and increases its virulence against resistant Salmonella enterica strains. Key mutations, particularly in the Long Tail

Preparing and preserving therapeutic phage suspensions is crucial for advancing phage therapy. By optimizing purification and formulation processes, this approach enhances phage shelf-life and

Phages must bypass various bacterial defenses, including restriction-modification (RM) systems, which degrade foreign DNA with specific motifs. We propose a novel method using random sequences

Bacteria produce numerous natural products to adapt to changing environments, but most of their functions are unknown. Genomic and synthetic biology studies reveal that some of these compounds,

Description of a novel approach to combat multidrug-resistant E. coli ST131 by combining a cocktail of bacteriophages with the C910 compound, which inhibits host cell invasion. This strategy

La course aux armements entre les phages et les bactéries a conduit au développement de divers mécanismes de défense pour les bactéries et de contre-mécanismes pour les phages. Alors que le nombre de

In my presentation, I summarize recent findings on the conservation of innate immune pathways between prokaryotes and eukaryotes. I show that bacterial defense mechanisms can in turn catalyze the