Cancer in the Global South - Cosavez-vous ? One Health

The "Cancer in the Global South" seminar will bring together various experts to discuss the current state of cancer research in the Southern regions. Speakers will address topics such as neglected molecular forms of cancer, environmental cancers, new approaches in the fight against cancer, and the relevance of "One Health" approaches. The aim is to provide a global perspective on the current situation of the fight against cancer in the South and to explore challenges and/or opportunities for future research. Presentations will be followed by a 30 minutes discussion session to allow participants to exchange ideas. This seminar will be of interest to researchers, anyone interested in cancer research from a global perspective, as well as those who wish to discover this research topic.

The seminar includes the following presentations: 

• State of play on cancers in the South: Martin Lajous (INSP Mexico) 
• Molecular forms of neglected cancer and environmental cancer: Stéphane Bertani (IRD, Peru) 
• New approaches, cancer and evolution: Frederic Thomas (CNRS CREEC, Montpellier) 
• Cancer and One Health approaches: Antoine Dujon (Deakin University, Australia) 
• Discussion / Conclusion (30 mins) 

MARTIN LAJOUS The aim of this presentation will be to provide an overview of the studies conducted on cancer in the South and to highlight the research perspectives to be developed. 

STEPHANE BERTANI The burden of cancer in developing countries is caused by a heterogeneous exposome that combines infectious pathogens and environmental exposures. This plight impacts the types of tumors developed, as well as their molecular correlates. Yet, the implementation of cancer control strategies depends on our understanding of the mechanisms associated with the oncogenesis and how they are influenced by the exposome. In this presentation, I will illustrate this situation by discussing the pathological and molecular peculiarities of liver cancer in Andean communities. 

FREDERIC THOMAS Cancer is a biological phenomenon that appeared about a billion years ago with the emergence of multicellular organisms. Approaching this disease with an evolutionary biology approach allows to better understand the origin of cancer, its biology and to improve therapies. 

ANTOINE DUJON This presentation will explain why cancer, which is an underestimated component of ecosystem functioning, should be integrated into the OneHealth framework and the implications for wildlife and human populations.