- 00:08>> Thomas Pradeu : Presentation
- 02:00>> Sven Saupe : Self, identity, fungi
- 03:49Biology of Self
- 04:44Fungi position in living world
- 06:19Fungi meeting...
- 07:04Mutual aversion, Incompatibility
- 09:05Mecanistic description of the working of one specific incompatibility system
- 13:27Symbolically invested terms, metaphors...
- 18:31>> Mathieu Paoletti : Self and non-self in fungi
- 18:51The fungal cell cycle
- 20:04Non self recognition
- 38:06>> Jonathan Visentin: Vegetative incompatibility vs Organ transplantation
- 38:51La transplantation d'organes
- 39:53Similitudes entre HLA et Het-e
- 42:07Différences entre HLA et Het-e
- 46:48- Subjectivité et émotions dans la recherche scientifique
- 49:02- Metaphor problem, Sokal affair...
- 54:50- Het-e, HLA and self recognition
- 57:09- Existence of receptors involved in the recognition of pathogens ?
- 57:39- Evolution and selective pressure / what is the driver : immunity or histocompatibility
- 1:01:46- Fungi involved in symbiosis ?
- 1:03:09- Tolerance mechanisms ?
- 1:04:31- Self and non-self : peut-on transposer le concept à la psychologie ?
- 1:11:20- Dissemination of the genes
Dans la même collectionPhilosophy of Science / Elliott Sober The cell as an elementary organism: from Schwann to Brücke and Kölliker What does a ‘global history’ of biology bring to us ? What’s Special About Genes? Causal Specificity, Information, and Genetic Host-Microbiota Symbiosis: One, Many, or Mega-Organism? Lessons from Internalism vs. Externalism ... Why Philosophy of Microbiology ?
Self and non-self in fungi
>> Sven Saupe : Self, identity, fungi
The notion of self is a rich but ambiguous concept that is used in a wide array of academic disciplines including immunology, psychology and philosophy (in particular in different branches of phenomenology). I would like to give an introduction to the application of this concept in the description of a cell-cell interaction phenomenon occurring in many if not all filamentous fungi and designated incompatibility. The term self non-self recognition is often used to classify this phenomenon thus stressing its likeness to other biological phenomena going under the same designation such as immune recognition or gamete recognition in plant allofertilization. After giving a direct description of incompatibility, I shall describe the molecular basis of a specific case of incompatibility mechanism involving a prion protein. Time permitting I would like to use the specific example of fungal incompatibility, to attempt to illustrate my impression of the role narration and symbolism (in the form of metaphors) play in the practice of research and textual rendition of scientific results.
>> Mathieu Paoletti : Self and non-self in fungi
Fungi are engaged in various biotic interactions requiring discrimination between self and nonhet loci defining incompatibility encode proteins displaying similarities with NOD Like Receptor (NLRs) of plant and animal innate immune systems. In the model species Podospora anserina genetic interactions between incompatible alleles of het-c and het-e mediate VI. het-e encodes a NLR protein while het-c codes for a glycolipid transfer protein. Evolutionary properties of these genes lead us to hypothesize that in addition to VI their products could function as fungal immune receptors following the guard model whereby HET-e recognizes alterations of HET-c as a consequence pathogen’s action. I will describe recently developed experimental models to assess HET-c and HET-e functions in detection of and response to hetero-specific non self. I will also briefly describe the huge repertoire of NLR encoded by fungal genomes that may be involved in non self recognition in different biotic interactions.
>> Jonathan Visentin : Vegetative incompatibility in fungi looks like graft rejection in human
- Date de réalisation : 12 Janvier 2016
- Durée du programme : 77 min
- Classification Dewey : Philosophie et psychologie, Philosophie et théorie de la biologie et des sciences de la vie
- Auteur(s) : SAUPE Sven, PAOLETTI Mathieu, VISENTIN Jonathan
- producteur : Université de Bordeaux - Service Audiovisuel et Multimédia
- Réalisateur(s) : Université de Bordeaux - Service Audiovisuel et Multimédia
- Editeur : Université de Bordeaux - Service Audiovisuel et Multimédia