Lieu de réalisation
Centre Inria d'Université Côte d'Azur
Langue :
Mustapha Khammash (Intervention)
Crédit image : Centre Inria d'Université Côte d'Azur
Détenteur des droits
Centre Inria d'Université Côte d'Azur
DOI : 10.60527/sk4k-5n90
Citer cette ressource :
Mustapha Khammash. Inria. (2024, 15 mars). Designing and Building Adaptive Genetic Control Systems. [Vidéo]. Canal-U. (Consultée le 13 juin 2024)

Designing and Building Adaptive Genetic Control Systems

Réalisation : 15 mars 2024 - Mise en ligne : 19 mars 2024
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The objective of this talk is to explore the fundamental problem of achieving RPA, focusing on a designated output variable and its robustness to perturbations across almost all network parameters. I will elucidate how RPA imposes critical structural constraints on underlying networks, characterized by simple linear algebraic conditions. These conditions provide insights into the diverse ways adaptation mechanisms can be realized.  I will relate these theoretical developments to practical implementation of RPA-achieving controllers and their applications. Specifically, I will discuss the implementation of new genetic RPA-achieving controllers within living cells and showcase their tunability and adaptation properties. Finally, I will highlight the relevance of these genetic control systems in the context of cell-based therapies.


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