Dr Jeba Jesudoss Chelladurai - P-glycoproteins of Toxocara canis: characterization of expression and pharmacological activity

To monitor and evaluate mass drug administration (MDA) programs for soil-transmitted helminths (STHs) the diagnostic standard is the microscopic detection of STH specific eggs in stool smears (Kato-

Crystal (Cry) proteins from Bacillus thuringiensis are used as effective insecticides. These pore forming toxins act within the midgut of insects killing them. Cry5B, has been found to target and

This presentation will provide an overview on recent investigations concerning the P-glycoprotein gene family in the equine roundworm Parascaris univalens. As prominent members of the ATP-Binding

Ascaris suum affects feed conversion and weight gain of pigs, but effects on intestinal microbiota remain largely unexplored. Therefore, the intestinal microbiome and metabolome was assessed in pigs

The intestine of nematode parasites is involved in more than digestion, absorption and storage of nutrients. It is involved in vesicular trafficking, ageing, innate immunity, drug metabolism and

In this talk I will review the progress in providing insight into fundamental aspects of Ascaris physiology and pharmacology and the experimental approaches that have been adopted and developed to

Despite global spread of anthelmintic resistance in livestock, there has been little discussion about the development of AR in poultry. Ascaridia galli has become ubiquitous in layers due to the ban

Ascarid parasites cause a massive burden on people in the developing world and on veterinary animals worldwide. We use a limited arsenal of anthelmintics to treat these infections. As the use of

Benzimidazole (BZ) resistance is rare in ascarids in contrast to strongyle parasites where this resistance is widespread. In strongyles, single nucleotide polymorphisms (SNPs) at codons 167, 198 and

Background: Ascariasis remains the most prevalent zoonotic helminthic disease affecting both humans and pigs and preventive chemotherapy continues to be the most widespread control method.

Management of nematode parasites of veterinary importance has become complicated because of the development of anthelmintic resistance. Resistance to benzimidazoles (BZ) is the most well characterized

Ligand-gated ion channels provide an excellent test for any expression system and for C. elegans as a model for parasitic nematode species, including the ascarids. They are complex proteins made of