Canal-U

Mon compte
LE STUDIUM Loire Valley Institute for Advanced Studies

Prof. Pieter Hiemstra - Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects


Copier le code pour partager la vidéo :
<div style="position:relative;padding-bottom:56.25%;padding-top:10px;height:0;overflow:hidden;"><iframe src="https://www.canal-u.tv/video/le_studium/embed.1/prof_pieter_hiemstra_antimicrobial_host_defence_peptides_immunomodulatory_functions_and_translational_prospects.57533?width=100%&amp;height=100%" style="position:absolute;top:0;left:0;width:100%;height: 100%;" width="550" height="306" frameborder="0" allowfullscreen scrolling="no"></iframe></div> Si vous souhaitez partager une séquence, indiquez le début de celle-ci , et copiez le code : h m s
Contacter la chaine
J’aime
Imprimer
partager facebook twitter

Prof. Pieter Hiemstra - Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects

Antimicrobial host defence peptides (AMPs) are effector molecules of the immune system. AMPs are considered as possible alternatives to conventional antibiotics for the treatment of respiratory infections, which is increasingly complicated by the problem of microbial antibiotic resistance. AMPs are also referred to as antimicrobial peptides and host defence peptides, and many AMPs were discovered based on their antimicrobial activity against a range of micro-organisms. However, they also display other activities that are relevant for host defence, including activities related to immune modulation and wound repair. Application of AMPs (and improved substitutes of these peptides) as a treatment for respiratory infections has been studied for some time, but they have not yet been introduced into the clinic. Direct administration of AMPs is complicated by e.g. cost of production and short half-life, and alternative strategies are considered. These include enhancement of their local production and activity. Nevertheless, there are a number of properties that make these peptides attractive candidates, including their broad-spectrum antimicrobial activity (possibly also including anti-SARS-CoV-2 activity), activity against multidrug resistant micro-organisms, and wide range of activities. In this presentation, recent developments in research on the role of these peptides in the lung, as well as their clinical use in novel therapies will be discussed.






  •  
  •  
    Date de réalisation : 24 Septembre 2020
    Durée du programme : 31 min
    Classification Dewey : Maladies des poumons (hypertension artérielle pulmonaire, hypertension pulmonaire, maladie obstructive respiratoire chronique, maladies respiratoires, ouvrages généraux sur les maladies des bronches et des poumons)
  •  
    Catégorie : Conférences
    Niveau : Tous niveaux médicaux
    Disciplines : Clinique médicale
    Collections : LE STUDIUM Conferences, Novel host- and microbiota-directed strategies for treating respiratory infections
    ficheLom : Voir la fiche LOM
  •  
  •  
    Langue : Anglais
    Mots-clés : peptide, immunologie
 

commentaires


Ajouter un commentaire Lire les commentaires
*Les champs suivis d’un astérisque sont obligatoires.
Aucun commentaire sur cette vidéo pour le moment (les commentaires font l’objet d’une modération)
 

Dans la même collection

 Juan Matos - H2 production on 1D and 2D Carbon-containing Fe-, Co, and Ni-based foamy catalysts.
 Athanasios G. Konstandopoulos - Material and Reactor Technologies for Solar Fuels
 Sixto Malato - Solar photocatalytic hydrogen production at pilot scale
 Pascal Brault - Reactive molecular dynamics simulations of H2 production and conversion
 Olivier Joubert - Brief Overview of Current French Hydrogen Research Activities, Focus on Materials
 Ally Aukaloo - From molecular to nanostructured materials for artificial photosynthesis
 Giuseppe Marci - Photocatalytic reduction of CO2 in gas-solid and in liquid-solid regimes
 Alejandro Anson-Casaos - Photoelectrochemical characterization of C/TiO2 and C/ZnO nanomaterials in aqueous electrolyte
 José Solla-Gullon - Recent advances and remaining challenges on the use of shape-controlled-metal nanoparticles in Electrocatalysis
 Christel Laberty-Robert - Impact of Electrodes Nanostructuration on Photoelectrochemical Performances
 Carlos Sanchez - Electrolyte engineering for electrochemical CO2 reduction
 Joaquim Faria - Carbon geometries as the base concept for developing efficient photocatalysts
 Geyla Dubed Bandomo - CO2 conversion with {Mn(CO)3Br} molecular sites into Covalent-Organic Frameworks
 Jesus Iniesta - Electrochemical and structural characterization of mixed matrix membrane coated electrodes for CO2 electroreduction
 Hermenegildo García - Getting closer to a large scale process. Photocatalysts for light-assisted CO2 hydrogenation
 Beatriz Avila - CO2 electroreduction to formate on Sn, Bi and Sb nanostructured electrodes: from fundamental studies to practical devices
 Prof. Marc McKee & Prof. Maxwell Hincke - Integrative workshop - Lessons learned and the path forward for innate immunity in biomineralization
 Dr Robbie Rae - Biological armour used to kill parasites
 Dr Christine Paillard - The Brown Ring disease in clams, a double-edged defense mechanism for shell disease recovery!
 Dr Sophie Berland - Probing the mechanical properties and biochemical defence offered by shell matrix proteins in bivalves
 Dr Frédéric Marin - Mollusk shell matrices: unexpected functions in biomineralization
 Dr Joël Gautron - Integrative workshop - Avian eggshell biomineralization and innate immunity
 Dr Natalie Reznikov - Application of deep learning for segmentation of 3D images in biomineralization
 Dr Claudine Blin - The innate immune function and diversity of osteoclasts
 Dr Nicolas Guyot - Phylogenetic and structural evolution of egg antimicrobial proteins and peptides
 Prof. Maxwell Hincke - The chroriallantoic membrane: insight from proteomics.
 Dr Ian Dunn - The genetics and function of the cuticle, the eggs antimicrobial outer barrier.
 Dr Sophie Réhault-Godbert - The eggshell microbiome
 Dr Liliana D’Alba - Eggshell mineralization in relation to nesting ecology in reptiles
 Prof. Alejandro Rodriguez Navarro - Mechanisms of eggshell biomineralization
 Prof. Marc McKee - The structure of avian (chicken) eggshell
 Prof. Bernd Kaspers - The developing immune system of the chicken embryo
 Dr Tim Badman - Natureculture approaches in the World Heritage Convention, and beyond.
 Dr Tim Jardine - Canada’s freshwater deltas as complex and vulnerable social-ecological systems.
 Nupur Prothi Khanna - Cultural landscapes of Water systems in Asia
 Dave Pritchard - Action for culture and the water environment through the Ramsar Convention on Wetlands
 Dr Avril Horne - Participatory environmental flows assessments
 Dr Erin O'Donnell - Reshaping the human relationship with water: what happens when a river becomes a person?
 Dr Wendy Monk & Prof. André St-Hilaire - Adapting social-cultural-environmental flows for cold regions.
 Dr Nathalie Richards - From the Mau Forest to Lake Victoria: The Journey of the Mara River in East Africa
 Dr Fengzhi He & Dr Rebecca Tharme - Freshwater megafauna: diversity, status, and cultural importance
 Dr Simone Langhans - Weaving together plural values in freshwater management: a case study of the Upper Clutha catchment in Aotearoa New Zealand
 Prof. Karl Wantzen - Development(s) of the River Culture Concept
 Prof. Angela Arthington - Progress with environmental flows to maintain healthy rivers and healthy societies
 Dr Elżbieta Sikora - Supercritical CO2 plant extracts as raw materials in modern cosmetic formulations
 Dr Magdalena Malinowska - Grape cane extracts a natural ingredients with cosmetic activities
 Dr Paweł Siudem - Aronia melanocarpa Fruits as a Dietary Source of bioactive compounds: 1H‑NMR, HPLC-DAD, and Chemometric Studies
 Dr Viviana Martins - Potential of vineyard calcium sprays to improve grape berry and wine quality
 Prof Régis Gougeon - Messages in a bottle: from oenolomics to the structural resolution of the transient chemistry of wine aging
 PANEL 5: NÉOLIBÉRALISME, AUTORITARISME ET NÉO-CONSERVATISME
 PANEL 6: THE CAPITALISM’S WAR ON HUMAN LIVES
 PANEL 4: LA VALEUR NÉOLIBÉRALE DE L’HUMAIN
 PANEL 3: LA VIOLENCE DU GOUVERNEMENT NÉOLIBÉRAL
 PANEL 2: LE NÉOLIBÉRALISME ET LA “GUERRE CIVILE MONDIALE"
 PANEL 1: THE NEOLIBERAL PANDEMIC (DIS)ORDER, CARING AND SOLIDARITIES
 Prof. Kingston Mills - Local T cells and their subversion in protective immunity to infection in the respiratory tract
 Prof. Adrian Martineau - Vitamin D in the prevention and treatment of respiratory infections
 Dr Antoine Guillon - Flagellin-based antibacterial strategy and clinical perspectives
 Prof. Mike Surette - The Good and the Bad of Commensal-Pathogen Interactions in the Airways
 Dr Raphaël Duivenvoorden - Trained Immunity as a novel therapeutic strategy
 Dr Mustapha Si-Tahar - Towards a metabolic anti-influenza therapy
 Dr Aurélie Crabbé - Host metabolites modulate bacterial susceptibility to antibiotics
 Dr Guido Santos - Multi-level computational modeling as a tool to understand molecular mechanisms behind bacterial lung infection
 Dr Rodrigo Guabiraba - Precision cut lung slices: a novel versatile tool to examine host–pathogen interactions in the chicken lung
FMSH
 
Facebook Twitter
Mon Compte